Dr CHEUNG Ka Shing, Michael

Dr Michael Chan

Clinical Assistant Professor

  • MBBS(HK) MPH(HK) MRCP(UK) FHKCP FHKAM (Medicine)
Biography

Dr Michael Ka Shing Cheung graduated from The University of Hong Kong in 2008, and received his Fellowship in Gastroenterology and Hepatology in 2015 from the Hong Kong College of Physicians. He obtained his Master of Public Health degree with distinction in 2016. He is currently the Clinical Assistant Professor in the Department of Medicine, the University of Hong Kong, Hong Kong. He is also the associate consultant in the University of Hong Kong-Shenzhen Hospital, Shenzhen, China, and honorary associate consultant in Queen Mary Hospital. Dr. Cheung’s research interests include gastric cancer, colorectal cancer, gut microbiota, gastrointestinal bleeding, and liver diseases (including hepatitis B virus, fatty liver, cirrhosis, hepatocellular carcinoma) with the use of Big Data analysis. He has published 66 international journal articles, including first-authored articles in Gut (impact factor 19.819), Gastroenterology (impact factor 17.373), Journal of the National Cancer Institute (impact factor 11.577), Diabetes Care (impact factor 16.019), Alimentary Pharmacology & Therapeutics (impact factor 7.515), Hypertension (impact factor 7.713), and Canadian Medical Association Journal (impact factor 7.744). He has given over 30 presentations (including oral plenary session) at international and local conferences and institutions.

Dr Cheung was awarded the Professor Anthony Hedley Prize in Public Health for the highest place in 2016. He received the APDWF/JGHG Young Investigator’s Award at Asian Pacific Digestive Week in 2017, Distinguished Research Paper Award for Young Investigator (2018 with Gold Medal Award, 2019 and 2020) from the Hong Kong College of Physicians, Faculty Outstanding Research Output Award (2018, 2019 and 2020) from the University of Hong Kong, Faculty Knowledge Exchange Award from the University of Hong Kong (2018), Best Abstract Award in Clinical Medicine in Medical Research Conference from the University of Hong Kong (2018, 2019 and 2020) as well as multiple other awards for abstract presentation in local and overseas conferences.

Dr Cheung received the Health and Medical Research Fund from the Research Grant Council, the Government of HKSAR to conduct a 2-year project (2019–2021) studying the epidemiology, risk factors and chemopreventive agents of post-colonoscopy colorectal cancer in Hong Kong. He was also the awardee of the Clinical Research Fellowship Programme and received the General Research Fund from the Research Grant Council, the Government of HKSAR to conduct a 2-year project (2021-2022) which was a randomized controlled trial on treating fatty liver disease.


Research Profile
  1. Big data analysis
  2. Epidemiology and chemoprevention of gastrointestinal and hepatobiliary cancers
  3. Gut microbiota
  4. Helicobacter pylori infection
  5. Gastrointestinal bleeding
  6. Liver diseases including hepatitis B virus infection and fatty liver

Selected Publications
  1. Cheung KS, Chan EW, Wong AYS, et al. Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: A population-based study. Gut 2018;67:28-35 (2019 impact factor 19.819)
  2. Cheung KS, Chen L, Chan EW, et al. Statins reduce the progression of non-advanced adenomas to colorectal cancer: a postcolonoscopy study in 187897 patients. Gut 2019;68:1979-1985 (2019 impact factor 19.819)
  3. Cheung KS, Hung IF, Chan PP, et al. Gastrointestinal manifestations of SARS-CoV-2 infection and virus load in fecal samples from the Hong Kong cohort and systematic review and meta-analysis. Gastroenterology 2020;159:81-95 (2019 impact factor 17.373)
  4. Cheung KS, Hung IF, Leung WK. Association between famotidine use and COVID-19 severity in Hong Kong. Gastroenterology 2020 [epub ahead of print] (2019 impact factor 17.373)
  5. Leung WK, Wong IOL, Cheung KS, et al. Effects of Helicobacter pylori Treatment on Incidence of Gastric Cancer in Older Individuals. Gastroenterology 2018;155:67-75 (2019 impact factor 17.373)
  6. Cheung KS, Chan EW, Chen L, et al. Diabetes mellitus increases risk of gastric cancer after Helicobacter pylori eradication: a territory-wide study with propensity score analysis. Diabetes Care 2019;42:1769-1775 (2019 impact factor 16.019)
  7. Cheung KS, Chan EW, Wong AYS, et al. Metformin use and gastric cancer risk in diabetic patients after Helicobacter pylori eradication. J Natl Cancer Inst 2019;111: 484-489 (2019 impact factor 11.577)
  8. Cheung KS, Chan EW, Wong AYS, et al. Aspirin and Risk of Gastric Cancer After Helicobacter pylori Eradication: A Territory-Wide Study. J Natl Cancer Inst 2018;110:743-749 (2019 impact factor 11.577)
  9. Cheung KS, Chan EW, Wong AYS, et al. ACE (Angiotensin converting enzyme) inhibitors/angiotensin receptor blockers are associated with lower colorectal cancer risk: a territory-wide study with propensity score analysis. Hypertension 2020 [epub ahead of print] (2019 impact factor 7.713)
  10. Cheung KS, Hung IF, Leung WK. Association between angiotensin blockade and COVID-19 severity in Hong Kong. CMAJ 2020;192:E635 (2019 impact factor 7.744)
  11. Cheung KS, Chen L, Chan EW, et al. Non-steroidal anti-inflammatory drugs but not aspirin are associated with a lower risk of post-colonoscopy colorectal cancer. Aliment Pharmacol Ther 2020;51:899-908 (2019 impact factor 7.515)
  12. Lyu Tao,* Cheung KS,* Ni L, et al. High prevalence and risk factors of multiple antibiotic resistance in patients who fail first-line Helicobacter pylori therapy in southern China: a municipality-wide multi-center, prospective cohort study. J Antimicrob Chemother 2020 (2019 impact factor 5.439) * co-first authorship
  13. Cheung KS, Seto WK, Lai CL, Yuen MF. Prevention and management of hepatitis B virus reactivation in cancer patients. Hepatol Int 2016;10:407-14 (2019 impact factor 5.102)
  14. Cheung KS, Chan EW, Wong AYS, et al. Statins were associated with a reduced gastric cancer risk in patients with eradicated Helicobacter pylori infection: a territory-wide propensity score matched study. Cancer Epidemiol Biomarkers Prev 2020;29:493-499 (2019 impact factor 4.344)
  15. Cheung KS, Mak LY, Liu SH, Cheng HM, Seto WK, Yuen MF, Lai CL. Entecavir vs tenofovir in hepatocellular carcinoma presentation in chronic hepatitis B infection: a systematic review and meta-analysis. Clin Transl Gastroenterol 2020 [epub ahead of print] (2019 impact factor 3.968)
  16. Cheung KS, Seto WK, Fung J, et al. Epidemiology and Natural History of Primary Biliary Cholangitis in the Chinese: A Territory-Based Study in Hong Kong between 2000 and 2015. Clin Transl Gastroenterol 2017;8:e116 (2019 impact factor 3.968)
  17. Cheung KS, Seto WK, Fung J, et al. Prognostic Factors for Transplant-Free Survival and Validation of Prognostic Models in Chinese Patients with Primary Biliary Cholangitis Receiving Ursodeoxycholic Acid. Clin Transl Gastroenterol 2017;8:e100 (2019 impact factor 3.968)
  18. Cheung KS, Seto WK, Leung WK. Application of Big Data analysis in gastrointestinal research. World J Gastroenterol 2019;25:2990-3008 (2019 impact factor 3.665)
  19. Cheung KS, Seto WK, Fung J, et al. Prediction of hepatocellular carcinoma development by aminotransferase to platelet ratio index in primary biliary cholangitis. World J Gastroenterol 2017;23:7863-7874 (2019 impact factor 3.665)
  20. Cheung KS, Seto WK, Fung J, et al. Epidemiology and natural history of Wilson's disease in the Chinese: A territory-based study in Hong Kong between 2000 and 2016. World J Gastroenterol 2017;23:7716-7726 (2019 impact factor 3.665)
  21. Cheung KS, Leung WK. Gastrointestinal bleeding in patients on novel oral anticoagulants: Risk, prevention and management. World J Gastroenterol 2017;23:1954-1963 (2019 impact factor 3.665)
  22. Cheung KS, Seto WK, Wong DK, et al. Relationship between HBsAg, HBcrAg and hepatocellular carcinoma in patients with undetectable HBV DNA under nucleos(t)ide therapy. J Viral Hepat 2017;24:654-661 (2019 impact factor 3.561)
  23. Cheung KS, Chen L, Seto WK, Leung WK. Epidemiology, characteristics and survival of post-colonoscopy colorectal cancer in Asia: a population-based study. J Gastroenterol Hepatol 2019;34:1545-1553 (2019 impact factor 3.437)

Awards
  1. Clinical Research Fellowship programme, Research Grant Council, The Government of HKSAR (2020/2021)
  2. Distinguished Research Paper Award for Young Investigator, Hong Kong College of Physicians (2020)
  3. Faculty Outstanding Research Output Award, The University of Hong Kong (2020)
  4. Best Abstract Award in Clinical Medicine in 25th Medical Research Conference (oral presentation), The University of Hong Kong (2020)
  5. Faculty Outstanding Research Output Award, The University of Hong Kong (2019)
  6. Travel Grant Award for oral abstract presentation, United European Gastroenterology Week (2019)
  7. Distinguished Research Paper Award for Young Investigator, Hong Kong College of Physicians (2019)
  8. Best Abstract Award in Clinical Medicine in 24th Medical Research Conference (oral presentation), The University of Hong Kong (2019)
  9. Faculty Outstanding Research Output Award, The University of Hong Kong (2018)
  10. Faculty Knowledge Exchange Award, The University of Hong Kong (2018)
  11. Sir Robert Black Trust Fund Postgraduate Scholarship (2018-2019)
  12. Distinguished Research Paper Award for Young Investigator (with Gold Medal Award), Hong Kong College of Physicians (2018)
  13. Best Poster Award, Silver Prize in 9th Asian-Pacific Topic Conference (2018)
  14. Best Abstract Award in Clinical Medicine in 23rd Medical Research Conference (oral presentation), The University of Hong Kong (2018)
  15. APDWF / JGHF Young Investigator’s Award, Asian Pacific Digestive Week (2017)
  16. Professor Anthony Hedley Prize in Public Health for highest place in Master of Public Health, The University of Hong Kong (2016)
  17. Distinction for both written exam and thesis in Master of Public Health, The University of Hong Kong (2016)
  18. Best Thesis Award for Exit Assessment Dissertations, Hong Kong College of Physicians (2015)

Grant Record

Competitive research grants as principal investigator

  1. General Research Fund, Research Grant Council, The Government of HKSAR, 2020/2021 (Ref no: 17110420; HKD $893,053)
  2. Health and Medical Research Fund, Food and Health Bureau, The Government of HKSAR, 2017 (Ref no: 16173001; HKD $619,520)
  3. Young Investigator Research Grant, Hong Kong College of Physicians, 2020 (HKD $50,000)
  4. Young Investigator Research Grant, Hong Kong College of Physicians, 2018 (HKD $50,000)
  5. Young Investigator Research Grant, Hong Kong College of Physicians, 2016 (HKD $50,000)