DIVISIONS/UNITS/CENTRES

Yong Pan, Xiaoyan Hui, Ruby Lai Chong Hoo, Dewei Ye, Cyrus Yuk Cheung Chan, Tianshi Feng, Yu Wang, Karen Siu Ling Lam and Aimin Xu , Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation,  Clin Invest. 2019;129(2):834-849.

Cheung CYY, Lee CH, Tang CS, Xu A, Au KW, Fong CHY, Ng KKK, Kwok KHM, Chow WS, Woo YC, Yuen MMA, Hai J, Tan KCB, Lam TH, Tse HF, Sham PC, Lam KSL., Genetic Regulation of Pigment Epithelium-Derived Factor (PEDF): An Exome-Chip Association Analysis in Chinese Subjects With Type 2 Diabetes., Diabetes. 2019 Jan;68(1):198-206. doi: 10.2337/db18-0500. Epub 2018 Oct 10.

Lee CH, Cheung CYY, Woo YC, Lui DTW, Yuen MMA, Fong CHY, Chow WS, Xu A, Lam KSL. Prospective associations of circulating adipocyte fatty acid-binding protein levels with risks of renal outcomes and mortality in type 2 diabetes. Diabetologia. 2019 Jan;62(1):169-177. doi: 10.1007/s00125-018-4742-8. Epub 2018 Sep 28.

Liu Z, Jin L, Yang JK, Wang B, Wu KKL, Hallenborg P, Xu A, Cheng KKY., The Dysfunctional MDM2-p53 Axis in Adipocytes Contributes to Aging-Related Metabolic Complications by Induction of Lipodystrophy., Diabetes. 2018 Nov;67(11):2397-2409. doi: 10.2337/db18-0684. Epub 2018 Aug 21.

Wang BLi ALi XHo PWWu DWang XLiu ZWu KKYau SSXu ACheng KK. ; Activation of hypothalamic RIP-Cre neurons promotes beiging of WAT via sympathetic nervous system.;  EMBO Rep. 2018 Apr;19(4). pii: e44977. doi: 10.15252/embr.201744977. Epub 2018 Feb 21.

Li HWu GFang QZhang MHui XSheng BWu LBao YLi PXu A Jia W.; Fibroblast growth factor 21 increases insulin sensitivity through specific expansion of subcutaneous fat.; Nat Commun. 2018 Jan 18;9(1):272. doi: 10.1038/s41467-017-02677-9.

Lee CH, Woo YC, Chow WS, Cheung CYY, Fong CHY, Yuen MMA, Xu A, Tse HF, Lam KSL. Role of Circulating Fibroblast Growth Factor 21 Measurement in Primary Prevention of Coronary Heart Disease Among Chinese Patients With Type 2 Diabetes Mellitus. J Am Heart Assoc. 2017 Jun 6;6(6). pii: e005344. doi: 10.1161/JAHA.116.005344.

Cheung CYY, Tang CS, Xu A, Lee CH, Au KW, Xu L, Fong CHY, Kwok KHM, Chow WS, Woo YC, Yuen MMA, Cherny SS, Hai J, Cheung BMY, Tan KCB, Lam TH, Tse HF, Sham PC, Lam KSL, An Exome-Chip Association Analysis in Chinese Subjects Reveals a Functional Missense Variant of GCKR That Regulates FGF21 Levels.Diabetes. 2017 Jun;66(6):1723-1728. doi: 10.2337/db16-1384. Epub 2017 Apr 6.

Hui X, Zhang M, Gu P, Li K, Gao Y, Wu D, Wang Y, Xu A, Adipocyte SIRT1 controls systemic insulin sensitivity by modulating macrophages in adipose tissue., EMBO Rep. 2017 Apr;18(4):645-657. doi: 10.15252/embr.201643184. Epub 2017 Mar 7.

Shu L, Hoo RL, Wu X, Pan Y, Lee IP, Cheong LY, Bornstein SR, Rong X, Guo J, Xu A, A-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroid hormones in brown adipocytes. Nat Commun. 2017 Jan 27;8:14147. doi: 10.1038/ncomms14147.

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