DIVISIONS/UNITS/CENTRES

Cheng CWLeong KWNg YMKwong YLTse E.; The peptidyl-prolyl isomerase PIN1 relieves cyclin-dependent kinase 2 (CDK2) inhibition by the CDK inhibitor p27.; ​J Biol Chem. 2017 Dec 29;292(52):21431-21441. doi: 10.1074/jbc.M117.801373. Epub 2017 Nov 8.

El-Khoueiry AB, Sangro B, Yau T, Crocenzi TS, Kudo M, Hsu C, Kim TY, Choo SP, Trojan J, Welling TH Rd, Meyer T, Kang YK, Yeo W, Chopra A, Anderson J, Dela Cruz C, Lang L, Neely J, Tang H, Dastani HB, Melero I. Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial. Lancet. 2017 Apr 20. pii: S0140-6736(17)31046-2. doi: 10.1016/S0140-6736(17)31046-2.

Chan TS, Lee YS, Del Giudice I, Marinelli M, Ilari C, Cafforio L, Guarini A, Tan D, Phipps C, Goh YT, Hwang W, Goh AZ, Siu LL, Wu S, Ha CY, Lin SY, Kwok CH, Lau CK, Wong KF, Foà R, Kwong YL, Tse E. Clinicopathological features and outcome of chronic lymphocytic leukaemia in Chinese patients.Oncotarget. 2017 Apr 11;8(15):25455-25468. doi: 10.18632/oncotarget.16037.

Ka-Wai Leong, Chi-Wai Cheng, Chun-Ming Wong, Irene Oi-Lin Ng, Yok-Lam Kwong, Eric Tse, miR-874-3p is down-regulated in hepatocellular carcinoma and negatively regulates PIN1 expression, Oncotarget, Advance Publications 2016

Alexander Kukalev, Yiu-Ming Ng, Limei Ju, Amal Saidi, Sophie Lane, Angeles Mondragon, Dirk Dormann, Sophie E. Walker, William Grey, Philip Wing-Lok Ho, David N. Stephens, Antony M. Carr, Karri Lamsa, Eric Tse and Veronica P. C. C. Yu, Deficiency of Cks1 Leads to Learning and Long-Term Memory Defects and p27 Dependent Formation of Neuronal Cofilin Aggregates, Cereb. Cortex (2016)

Piao W, Chau D, Yue LM, Kwong YL, Tse E, Arsenic trioxide degrades NPM-ALK fusion protein and inhibits growth of ALK-positive anaplastic large cell lymphoma, Leukemia. 2016 Nov 18. doi: 10.1038/leu.2016.311. 

Lam SS, Ho ES, He BL, Wong WW, Cher CY, Ng NK, Man CH, Gill H, Cheung AM, Ip HW, So CC, Tamburini J, So CW, Ho DN, Au CH, Chan TL, Ma ES, Liang R, Kwong YL, Leung AY, Homoharringtonine (omacetaxine mepesuccinate) as an adjunct for FLT3-ITD acute myeloid leukemia, Sci Transl Med. 2016 Oct 5;8(359):359ra129.



Prof. KWONG YL; 2016/17; Theme-based Research Scheme (TRS); T12-401/16-W; 51000; Plasma DNA as a Platform Technology for Cancer Detection

Dr. TSE EWC; 2016/17; S.K. Yee Medical Foundation Grants; 2161212; 888000; Provision of obinutuzumab (anti-CD20 monoclonal antibody) to delderly and/or unfit patients with chronic lymphocytic leukaemia

Prof. LEUNG AYH; 2016/17; S.K. Yee Medical Foundation Grants; 2161210; 700000; Provision of free decitabine for young patients with acute myeloid leukemia (AML) carrying DNMT3A mutation