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A photo of Prof YUEN Man Fung
Prof YUEN Man Fung
Deputy Head of Department
Li Shu Fan Medical Foundation Professor in Medicine
Chair of Gastroenterology and Hepatology
MBBS, MD, PhD, FRCP (Edin), FRCP (Glasg), FRCP (Lond), FHKCP, FHKAM (Med)
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Professor Man-Fung Yuen is the Chair Professor and Endowed Professor in Medicine of the Li Shu Fan Medical Foundation, the Chief of the Division of Gastroenterology and Hepatology and the Deputy Chief of Service of the Department of Medicine, Queen Mary Hospital, Hong Kong and the Assistant Dean of the Faculty of Medicine, the University of Hong Kong. Professor Yuen's research interests include the prevention, natural history, molecular virology and treatment of chronic hepatitis B and C, and hepatocellular carcinoma. He has published more than 280 research papers. He has received several prestigious awards including the Outstanding Young Researcher Award in 2005 and Outstanding Researcher Award in 2010 by The University of Hong Kong, the JGH Emerging Leader Lectureship Award in 2006 by 4 major Asia Pacific Gastroenterology and Hepatology Associations, and the Winner of Young Scientist Award in 2008 by the Association of Southeast Asian Institutions of Higher Learning (ASAIHL) – Scopus. According to BiomedExperts, he is now the third top author for publications related to chronic hepatitis B disease in the world. He is the top 1% scientists in clinical medicine according to the ISI Web of Knowledge. His H-index is 52, 43 and 62 according to Scopus, ResearcherID and Google Scholar Citations respectively. He is the editor for four international journals and the editorial members for many international journals.


Selected Publications

  1. Seto WK, Wong DK, Fung J, Hung IF, Fong DY, Yuen JC, Tong T, Lai CL, Yuen MF. A large case-control study on the predictability of hepatitis B surface antigen (HBsAg) levels three years before HBsAg seroclearance. Hepatology 2012;56:812-9.
  2. Wong DKH, Huang FY, Lai CL, Poon RTP, Seto WK, Fung J, Hung IFN, Yuen MF. Occult hepatitis B infection and HBV replicative activity in patients with cryptogenic cause of hepatocellular carcinoma. Hepatology 2011;54:829-36.
  3. Yang HI, Yuen MF, Chan HLY, Han KH, Chen PJ, Kim DY, Ahn SH, Chen CJ, Wong VWS, Seto WK. Risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B): development and validation of a predictive score. Lancet Oncology 2011;12:568-74.
  4. Yuen MF, Wong DK, Lee CK, Tanaka Y, Allain JP, Fung J, Leung J, Lin CK, Sugiyama M, Sugauchi F, Mizokami M, Lai CL. Transmissibility of Hepatitis B Virus (HBV) Infection through Blood Transfusion from Blood Donors with Occult HBV Infection. Clin Infect Dis 2011; 52:624-32.
  5. Yuen MF, Han KH, Um SH, Yoon SK, Kim HR, Kim J, Kim CR, Lai CL. Antiviral activity and safety of LB80380 in hepatitis B e antigen-positive chronic hepatitis B patients with lamivudine-resistant disease. Hepatology 2010; 51:767-76.
  6. Yuen MF, Fung J, Wong DK, Lai CL. Prevention and management of drug resistance for antihepatitis B treatment. Lancet Infect Dis 2009;9(4):256-64.
  7. Yuen MF, Wong DKH, Fung J, Ip P, But D, Hung I, Lau K, Yuen JCH, Lai CL. HBsAg seroclearance in chronic hepatitis B in Asian patients: replicative level and risk of hepatocellular carcinoma. Gastroenterology 2008;135:1192-9.
  8. Lai CL, Yuen MF. Chronic hepatitis B -- new goals, new treatment. N Engl J Med 2008;359:2488-91.
  9. Lai CL, Yuen MF. The natural history and treatment of CHB: critical evaluation of treatment criteria and endpoints. Ann Intern Med 2007;147:58-61
  10. Poynard T, Yuen MF, Ratziu V, Lai CL. Viral hepatitis C. The Lancet 2003;362(9401):2095-100
  11. Lai CL, Ratziu V, Yuen MF, Poynard T. Viral hepatitis B. The Lancet 2003;362(9401):2089-94.
  12. Yuen MF, Lai CL. Treatment for chronic hepatitis B. The Lancet Infect Dis 2001;1:232-41.

Grant Record

Project Code/Funding Scheme Project Title/Principal Investigator/Department Approved Amount (HK$)
Research Grant Council (RGC GRF), Hong Kong, 2009 - 2010 Genetic and epigenetic analyses of occult hepatitis B virus infection $661,290
Research Grant Council (RGC GRF), Hong Kong, 2008 - 2009 Transmissibility of hepatitis B virus infection from blood donors with occult hepatitis B infection $566,592
Research Fund for the Control of Infectious Diseases (RFCID), Hong Kong Special Administration Region (HKSAR), 2009 - 2010 Virological and clinico-pathological factors in estimating the chance of recurrence of hepatocellular carcinoma after surgical resection in patients with chronic hepatitis B $699,110

Key Offices

  • Chief, Division of Gastroenterology & Hepatology, The University of Hong Kong, Queen Mary Hospital, Hong Kong
  • Assistant Dean, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong
  • Deputy Chief of Service, Department of Medicine, Queen Mary Hospital, Hong Kong
  • Chairman, Clinical Ethics & Professional Standard Committee, Hong Kong West Cluster, Hospital Authority
  • Member, Supplementary Medical Professions Council, Food and Health Bureau, Government Secretariat, The Government of the Hong Kong Special Administrative Region, The People's Republic of China
  • Member, Examination Sub-committee of Licentiate Committee of Medical Council of Hong Kong, Hong Kong
  • Programme Director, Specialty Board of Gastroenterology and Hepatology of Hong Kong Region, Hong Kong College of Physicians

Esteem Measures

  • Winner of Young Scientist Award 2008 (competition among 24 nominations of researchers from different countries in Asian Pacific region in the category of Medicine). Association of Southeast Asian Institutions of Higher Learning (ASAIHL) – Scopus
  • Winner of Sir David Todd Lectureship 2012, Hong Kong College of Physicians
  • Ranked as the third top author in the world for chronic hepatitis B in BiomedExperts 2011 (
  • Invited reviewer for Wellcome Trust fellowship, Neuroscience and Mental Health, The Wellcome Trust, 215 Euston Road, London NW1 2BE, United Kingdom,, 2013

Editorial Board Memberships

  • Hepatitis Research and Treatment
  • Journal of Gastroenterology and Hepatology
  • Hepatology International
  • Internal Medicine
  • Journal of Clinical and Translational Hepatology