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A photo of Dr CHEUNG Yu Yan, Chloe
Dr CHEUNG Yu Yan, Chloe
Research Assistant Professor
PhD (HKU), MPH(HKU)
an email logo cyy0219@hku.hk
a telephone logo 39179746
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Biography

Dr. Cheung obtained her PhD degree (2011) and MPH degree (2017) from the University of Hong Kong. She is currently a Research Assistant Professor in the Department of Medicine, the University of Hong Kong.

ORCID: https://orcid.org/0000-0002-7884-5295

Research Profile

Research interests of Dr. Cheung includes genetics of cardiovascular diseases, obesity, type 2 diabetes and its related complications

Selected Publications

  1. Cheung CY, Tso AW, Cheung BM, Xu A, Ong KL, Fong CH, Wat NM, Janus ED, Sham PC, Lam KS 2010 Obesity susceptibility genetic variants identified from recent genome-wide association studies: implications in a Chinese population. J Clin Endocrinol Metab 9:139-1403.
  2. Cheung CY, Tso AW, Cheung BM, Xu A, Ong KL, Law LS, Wat NM, Janus ED, Sham PC, Lam KS 2011 Genetic variants associated with persistent central obesity and the metabolic syndrome in a 12-year longitudinal study. Eur J Endocrinol 164:381-388.
  3. Cheung CY, Tso AW, Cheung BM, Xu A, Fong CH, Ong KL, Law LS, Wat NM, Janus ED, Sham PC, Lam KS 2011 The KCNJ11 E23K polymorphism and progression of glycaemia in Southern Chinese: a long-term prospective study. PLoS ONE 6:e2898
  4. Yaghootkar H, Lamina C, Scott RA, Dastani Z, Hivert MF, Warren LL, Stancakova A, Buxbaum SG, Lyytikainen LP, Henneman P, Wu Y, Cheung CY, Pankow JS, Jackson AU, Gustafsson S, Zhao JH, Ballantyne CM, Xie W, Bergman RN, Boehnke M, El Bouazzaoui F, Collins FS, Dunn SH, Dupuis J, Forouhi NG, Gillson C, Hattersley AT, Hong J, Kahonen M, Kuusisto J, Kedenko L, Kronenberg F, Doria A, Assimes TL, Ferrannini E, Hansen T, Hao K, Haring H, Knowles JW, Lindgren CM, Nolan JJ, Paananen J, Pedersen O, Quertermous T, Smith U, Lehtimaki T, Liu CT, Loos RJ, McCarthy MI, Morris AD, Vasan RS, Spector TD, Teslovich TM, Tuomilehto J, Willems van Dijk K, Viikari JS, Zhu N, Langenberg C, Ingelsson E, Semple RK, Sinaiko AR, Palmer CN, Walker M, Lam KS, Paulweber B, Mohlke KL, van Duijn C, Raitakari OT, Bidulescu A, Wareham NJ, Laakso M, Waterworth DM, Lawlor DA, Meigs JB, Richards JB, Frayling TM 2013 Mendelian Randomisation Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes. Diabetes 62(10):389-98.  
  5. Cheung CY, Hui EY, Cheung BM, Woo Y, Xu A, Fong CH, Ong KL, Yeung C, Janus ED, Tse HF, Sham PC, Lam KS 2014 Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study. Eur J Endocrinol 171(1):107-11.  
  6. Lee CH, Cheung CY, Chow WS, Woo YC, Yeung CY, Lang BH, Fong CH, Kwok KH, Chen SPL, Mak CM, Tan KC, Lam KS 2015 Genetics of apparently sporadic pheochromocytoma and paraganglioma in a Chinese population. Horm Metab Res. 47(11):833-838.  
  7. Tang CS, Zhang H, Cheung CY (co-first author), Xu M, Ho JC, Zhou W, Cherny SS, Zhang Y, Holmen O, Au KW, Yu H, Xu L, Jia J, Porsch RM, Sun L, Xu W, Zheng H, Wong LY, Mu Y, Dou J, Fong CH, Wang S, Hong X, Dong L, Liao Y, Wang J, Lam LS, Su X, Yan H, Yang ML, Chen J, Siu CW, Xie G, Woo YC, Wu Y, Tan KC, Hveem K, Cheung BM, Zöllner S, Xu A, Chen EY, Jiang CQ, Zhang Y, Lam TH, Ganesh SK, Huo Y, Sham PC, Lam KS, Willer CJ, Tse HF, Gao W. 2015 Exome-wide Association Analysis Reveals Novel Coding Sequence Variants Associated with Lipid Traits in Chinese. Nat Commun 6: 10206
  8. Cheung CY, Hui EY, Lee CH, Kwok KH, Gangwani R, Li KK, Chan JC, Woo YC, Chow WS, Yuen MM, Wong RL, Fong CH, Xu A, Wong DS, Sham PC, Lam KS. 2016 Impact of genetic loci identified in genome-wide association studies on diabetic retinopathy in Chinese patients with type 2 diabetes. Invest Ophthalmol Vis Sci. 57(13):5518-5524
  9. Cheung CY, Tang CS, Xu A, Lee CH, Au KW, Xu L, Fong CH, Kwok KH, Chow WS, Woo YC, Yuen MM, Hai JS, Jin YL, Cheung BM, Tan KC, Cherny SS, Zhu F, Zhu T, Thomas GN, Cheng KK, Jiang CQ, Lam TH, Tse HF, Sham PC, Lam KS. 2017 Exome-chip association analysis reveals an Asian-specific missense variant in PAX4 associated with type 2 diabetes in Chinese individuals. Diabetologia 60:107-115
  10. Cheung CY, Tang CS, Xu A, Lee CH, Au KW, Xu L, Fong CH, Kwok KH, Chow WS, Woo YC, Yuen MM, Cherny SS, Hai JS, Cheung BM, Tan KC, Lam TH, Tse HF, Sham PC, Lam KS 2017 An exome-chip association analysis in Chinese subjects reveals a functional missense variant of GCKR that regulates FGF21 levels. Diabetes 66(6):1723-1728
  11. Lee CH, Woo YC, Chow WS, Cheung CY, Fong CH, Yuen MM, Xu A, Tse HF, Lam KS 2017 Role of Circulating Fibroblast Growth Factor 21 Measurement in Primary Prevention of Coronary Heart Disease Among Chinese Patients With Type 2 Diabetes Mellitus. J Am Heart Assoc. 6;6(6). pii: e005344
  12. Lu X, Peloso GM, Liu D, Wu Y, Zhang H, Zhou W, Li J, Tang CS, Dorajoo R, Li H, Long J, Guo X, Xu M,  Spracklen CN, Chen Y, Liu X, Zhang Y, Khor CC, Liu JJ, Sun L, Wang L, Gao YT, Hu Y, Yu K, Wang Y, Cheung CY, Wang F, Huang J, Fan Q, Cai Q, Chen S, Shi J, Yang X, Zhao W,  Sheu WHH, Cherny SS,  He M, Feranil  AB, Adair LS,  Gordon-Larsen P,  Du S,  Varma R, Chen  IYD, Shu X, Lam KSL, Wong TY,  Ganesh SK, Mo Z,  Hveem K, Fritsche  L, Nielsen JB, Tse HF, Huo Y,  Cheng CY,  Chen YE, Zheng W, Tai ES, Gao W, Lin X, Huang W, Abecasis G, GLGC Consortium, Kathiresan S,  Mohlke KL, Wu T, Sham PC,  Gu D, Willer CJ 2017 Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants contributing to lipid levels and coronary artery disease. Nat Genet 49(12):1722-1730
  13. Lee CH, Cheung CY, Woo YC, Lui DTW, Yuen MMA, Fong CHY, Chow WS, Xu A, Lam KSL 2018 Circulating Adipocyte Fatty Acid-Binding Protein Concentrations Predict Multiple Mortality Outcomes among Men and Women with Diabetes. Clin Chem. (Epub ahead of print)
  14. Wong YK, Cheung CY, Tang CS, Au KW, Hai JS, Lee CH, Lau KK, Cheung BMY, Sham PC, Xu A, Lam KS, Tse HF 2018 Age-Biomarkers-Clinical (ABC) Risk Factors for Prediction of Cardiovascular Events in Patients with Coronary Artery Disease. ATVB. (Epub ahead of print)