Full integration of specialty services in the previous University Medical Unit (UMU) and Government Medical Unit (GMU) was completed in 1994/95. Integration of medical staff duties was started in September 1995 and large part of this was completed at the end of 1995/96.

The high standard of service in each of the specialties have been maintained in all existing and new activities. Each division offers a range of specialist services. The Department provides specialty clinical services in 12 Divisions. Further information on each of the Specialty Divisions are list in each of their own Specialty Divisions' homepages.

Many of these services represent ground-breaking efforts in Hong Kong. The Department has pioneered care in many innovative areas including:

• invasive cardiac procedures such as coronary angioplasty and radiofrequency catheter ablation, innovative cardiac pacing;
• the first prenatal diagnosis and genetic counselling centre for thalassaemia, haemophilia and neurodegenerative diseases in SE Asia and the only one in Hong Kong to date;
• Hong Kong's first bone marrow and peripheral stem cell transplants;
• physician support for Hong Kong's first liver, heart and lung transplants;
• protocol chemotherapy for leukaemia, lymphoma and advanced lung cancer;
• the first endoscopic retrograde cholangiopancreatography service, the first endoscopic sphincterotomy service for bile duct stones as well as the first biliary stenting service for malignant jaundice. 

• the programme for refractory epilepsy with EEG telemetry and comprehensive pre-surgical evaluation & the Acute Stroke Unit;
• comprehensive cardiac, pulmonary, and renal rehabilitation programmes;
• the development of dedicated well-woman and diabetic clinics in community practice and the establishment of the Centre of Education and Research in Family Medicine,
• the KK Leung Diabetes Centre, and
• the Simon KY Lee Digestive Disease Laboratory, which is the first laboratory in Asia using the 13C Mass Spectrometer to detect Helicobacter pylori infection of the stomach.
• Francis R. Zimmern Centre for Cardiology, the Mong Man Wai Cardiac Catheterization Laboratory