Medical Research Conference

You are cordially invited to attend the 26th Medical Research Conference. This annual research conference aims at fostering intra-department, inter-department/school and inter-university collaborations in research.


Organising Committee

Chairman
Prof Wai Kay Seto

Members
Dr Joanne Chiu
Prof Ivan Hung

Dr Gary Lau
Dr Paul Lee
Dr Philip Li
Dr Judith Mak
Prof Eric Tse
Dr Desmond Yap


e-Poster

e-Poster Oral Presentation List

Clinical Research

Ab No Specialty / Division Author Abstract Title Presentation File
27 Gastroenterology and Hepatology Dr Mak Lung-Yi Loey Reduced hepatic steatosis is associated with higher risk of hepatocellular carcinoma in chronic hepatitis B infection  pdf
66 Gastroenterology and Hepatology Dr Cheung Ka Shing Association between antibiotic use and colorectal cancer development: a territory- wide study  pdf
2 Rheumatology and Clinical Immunology Dr Li Philip Hei Territory-wide epidemiology and sensitisation patterns of beta-lactam allergy in Hong Kong  pdf
16 Gastroenterology and Hepatology Dr Lui Ka Luen Machine learning model in predicting the minimal endoscopy services requirement for gastrointestinal cancer diagnosis in Hong Kong during various phases of COVID-19  pdf
23 Cardiology Li Hang Long Outcomes and microbiology in patients with infective endocarditis in Hong Kong 1996 to 2019  pdf
48 Haematology, Medical Oncology and Haemopoietic Stem Cell Transplantation Lam Tsun Ho Outcomes of allogeneic haematopoietic stem cell transplant for acute lymphoblastic leukaemia/lymphoma in Hong Kong: a retrospective study  pdf
49 Neurology Yeung Elton Hau Lam Neurological observation assistant in healthcare: classifying postures and estimating disability of neurological in-patients using wearable inertial sensors  pdf
57 Respiratory Medicine and Critical Care Medicine Dr Yeung Pui Ning Pauline Predictors of favourable neurological outcomes in a territory-first extracorporeal cardiopulmonary resuscitation programme  pdf
65 Haematology, Medical Oncology and Haemopoietic Stem Cell Transplantation Tsui Sze Pui Redefining prognostication of de novo cytogenetically normal acute myeloid leukaemia in young adults  pdf
86 Cardiology Zhou Mi Myocardial strain analysis in uncomplicated COVID-19 survivor  pdf

 

Basic Science & Translational

Ab No Specialty / Division Author Abstract Title Presentation File
12 Endocrinology and Metabolism Yan Xingqun Novel role of GDF15 in non-alcoholic steatohepatitis  pdf
29 Nephrology Lok Wing Yan The PAR-1 antagonist Vorapaxar protects against kidney injury and tubulointerstitial fibrosis in the progression of AKI to CKD  pdf
31 Gastroenterology and Hepatology Wang Lingling Shifts in gut antibiotic resistance genes after the exposure to different H pylori eradication therapies  pdf
33 Rheumatology and Clinical Immunology Ma Jie Dysregulation of interleukin-18 receptor accessory protein in neutrophils of patients with systemic lupus erythematosus  pdf
38 Endocrinology and Metabolism Feng Tianshi Adipocyte-derived lactate potentiates obesity-evoked adipose macrophage inflammation  pdf
41 Neurology Yick Leung Wah Pioglitazone ameliorates motor impairments and spinal cord pathologies in a mouse model of neuromyelitis optica spectrum disorders  pdf
43 Cardiology Wei Rui CRISPR-targeted genome editing of human induced pluripotent stem cells-derived hepatocytes for treatment of Wilson’s disease  pdf
47 Nephrology Xue Rui Lipopolysaccharide induces Nuclear Paraspeckle Assembly Transcript 1 expression in acute kidney injury via TLR4/NF-κB signalling  pdf
91 Respiratory Medicine and Critical Care Medicine Kwok Hoi Hin Nicotinic acetylcholine receptor subunit alpha 7 mediates cigarette smoke-induced PD-L1 expression in human bronchial epithelial cells  pdf


e-Poster Presentation List

Clinical Research

Ab No Specialty / Division Author Abstract Title Presentation File
01 Respiratory Medicine and Critical Care Medicine Kwok Wang Chun Clinical characteristics in patients with non-cystic fibrosis bronchiectasis and co-existing airway diseases in Chinese population  pdf
09 Gastroenterology and Hepatology Guo Chuanguo Associations of seasonal variations and meteorological parameters with incidences of upper and lower gastrointestinal bleeding in older adults  pdf
17 Gastroenterology and Hepatology Guo Chuanguo Aspirin use and risk of colorectal cancer among older adults  pdf
25 Pharmacoepidemiology Fan Min Postmarket safety of orphan drugs: a longitudinal analysis of United States Food and Drug Administration database between 1999 and 2018  pdf
26 Neurology Yam Ka Keung Pilot study of smartphone-based applications in assessing motor and gait disability in Parkinson’s disease  pdf
28 Gastroenterology and Hepatology Mak Lung-Yi Loey Persistently detectable serum HBV DNA and HBV pgRNA is associated with hepatocellular carcinoma development in chronic hepatitis B patients receiving long-term nucleoside analogue therapy  pdf
30 Endocrinology and Metabolism Geng Leiluo Intractable hypoglycaemia induced by the antibody against exogenous insulin in a Chinese patient with type 1 diabetes  pdf
34 Haematology, Medical Oncology and Haemopoietic Stem Cell Transplantation Ng Yuey Zhun Haploidentical haematopoietic stem cell transplant outcomes from Queen Mary Hospital  
40 Cardiology Lam Lok Yee Jane Clinical outcome following percutaneous coronary intervention in stable coronary artery disease based on a novel index: computational pressure-flow dynamics derived fractional flow reserve  pdf
46 Cardiology Ng Andrew Kei-Yan Association between contrast induced nephropathy after percutaneous coronary intervention and major adverse cardiac events  
59 Cardiology Tse Yi Kei Stephanie Prognostic value of right ventricular remodelling and function in patients undergoing concomitant mitral and aortic valve surgery  pdf
63 Cardiology Yu Si Yeung Association of statin with 1-year mortality in patients with infective endocarditis  pdf
64 Cardiology Yu Shuk Yin Prognostic value of cirrhotic features detected by ultrasound in patients undergoing tricuspid annuloplasty  pdf
71 Geriatrics Chan Tuen Ching Prevalence of foot problems in Hong Kong long-term care facility residents  
73 Rheumatology and Clinical Immunology Cheung Chung Ting Amy Malignancies in spondyloarthritis with and without concomitant psoriasis, and the effect of disease-modifying anti-rheumatic drugs  pdf
75 Rheumatology and Clinical Immunology Lam Ho Ming Risk of tuberculosis in patients with spondyloarthritis: data from a centralised electronic database in Hong Kong  pdf
77 Haematology, Medical Oncology and Haemopoietic Stem Cell Transplantation Leung Garret Phase II single-arm open-labelled study evaluating combination of quizartinib and omacetaxine mepesuccinate in newly diagnosed or relapsed/refractory acute myeloid leukaemia carrying Fms-like tyrosine kinase 3  
80 Neurology Teo Kay Cheong Benefit and risk of lower follow-up blood pressure after intracerebral haemorrhage  pdf
82 Cardiology Ren Qing-Wen Statin use is associated with lower cancer risk and cancer-related mortality in patients with heart failure: a territory-wide study  pdf
94 Endocrinology and Metabolism Kan Ka Chun Andy Serum adipocyte fatty acid-binding protein level predicts heart failure hospitalisation in type 2 diabetes: a prospective cohort study  pdf

 

Basic Science & Translational Research

Ab No Specialty / Division Author Abstract Title Presentation File
04 Rheumatology and Clinical Immunology Li Man Hon Jimmy First report of pathogenic mutations and complete C6 deficiency in Chinese pedigree  
08 Endocrinology and Metabolism Liao Boya Identification of a novel therapeutic target for cerebral ischaemia injury: role of branched chain amino acids catabolism in ischaemic stroke  pdf
10 Pharmacoepidemiology Yu Qiuyan Impact of childhood pneumococcal conjugate vaccine immunisation on all-cause pneumonia admissions: a 14-year population-based interrupted time series analysis  pdf
11 Gastroenterology and Hepatology Huang Fung Yu Tumour suppressive role of sirtuin 4 in induction of G2/M arrest and apoptosis in HBV-related hepatocellular carcinoma  pdf
32 Rheumatology and Clinical Immunology Chow Jia Xin Delineating interferon-alpha mediated AIM2 inflammasome response in systemic lupus erythematosus  
37 Endocrinology and Metabolism Wang Yao Soluble interleukin-6 receptor determines exercise responsiveness in term of insulin sensitivity and glycemic control  pdf
39 Neurology Chang Eun Seo (Eunice) Long-term pharmacological inhibition of mutant leucine-rich repeat kinase 2 hyperactivity reduced alpha-synuclein serine-129 phosphorylation and oligomer levels in mouse brains  pdf
42 Neurology Malki Yasine Age-related expression and activity profile of glucocerebrosidase in brain and the association with phosphorylated alpha-synuclein implicated in Parkinson’s disease  pdf
51 Respiratory Medicine and Critical Care Medicine Khan Mahjabin Anti-neoplastic impact of thymoquinone from Nigella Sativa on Small Cell Lung Cancer  pdf
52 Respiratory Medicine and Critical Care Medicine Feng Yuqian Interleukin-9 triggers strong antitumor immune response thus inhibiting lung cancer growth  pdf
53 Endocrinology and Metabolism Peng Jiaxing Bioproduction and reconstruction of anti-C-reactive protein monoclonal antibody  pdf
54 Clinical Pharmacology Fei Yue Using an artificial neural network to identify the population at risk of obesity in the United States  pdf
67 Respiratory Medicine and Critical Care Medicine Lam Sze Kwan Combination effect of dichloroacetate and niclosamide in malignant pleural mesothelioma cells  
76 Cardiology Ho Wai In Liposome-embedded curcumin alleviates liver injury in Atp7b-/-Wilson disease mouse model  pdf
79 Haematology, Medical Oncology and Haemopoietic Stem Cell Transplantation Kwok Tsz Ho Homoharringtonine overcame drug resistance and showed synergism with venetoclax in the treatment of acute myeloid leukaemia  pdf
81 Respiratory Medicine and Critical Care Medicine Chen Rui Effect of cigarette smoke on airway inflammation, mucus hypersecretion and endoplasmic reticulum stress in a three-dimensional co-culture model of airway epithelium and smooth muscle  
84 Clinical Pharmacology Fei Yue Using an artificial neural network to identify the population at risk of type 2 diabetes mellitus in the United States  pdf
88 Haematology, Medical Oncology and Haemopoietic Stem Cell Transplantation Chan Yuen Ki Polo-like kinase 4 inhibitor suppresses hepatocellular carcinoma through inducing extensive polyploidy and activating STING pathway  pdf
90 Respiratory Medicine and Critical Care Medicine Liang Yingmin Effect of fine particulate matter (PM2.5) collected in Hong Kong on mitochondrial permeability transition pore in human airway epithelial cells pdf 
92 Neurology Ma Ka Fai Oscar CMF-019 elevates neuronal insulin sensitivity: an implication of therapeutic potential of Alzheimer’s disease  pdf

 


Program

TIME
Activity
09:00 – 09:20
Registration
09:20 – 09:30
Opening Remarks by Prof Chak Sing Lau, Head, Department of Medicine
09:30 – 09:40
Speech by Prof Wai Kay Seto, Chairman of 26th MRC
09:40 – 09:55

New Developments at CPOS for Medical Research

Chairman: Prof Wai Kay Seto

Dr Agnes Chan, Centre Manager, Centre for PanorOmic Sciences, HKU
09:55 – 10:10

Current Developments and Future Directions in Advancing Comparative Medicine Research

Chairman: Prof Wai Kay Seto

Dr Dewi Rowlands, Head, Centre for Comparative Medicine Research, HKU

10:10 – 11:30

Sequencing Techniques and Advances

Chairmen: Prof Eric Tse & Dr James Ho

1. Advanced sequencing and analysis for studying viral infection and transmission - Dr Tommy Lam, Assistant Professor, School of Public Health, HKU

2. Next Generation Sequencing – Diagnosing undiagnosed diseases and beyond - Dr Brian Chung, Clinical Associate Professor, Department of Paediatrics and Adolescent Medicine, HKU

3. The application of high-throughput sequencing in clinical microbiology - Dr Gilman Siu, Associate Professor, Department of Health Technology and Informatics, PolyU

4. Gene sequencing in Haematological Malignancies – Advances and Clinical Applications - Dr Harry Gill, Clinical Assistant Professor, Department of Medicine, HKU

11:30 – 11:50
Break
11:50 – 12:50

Gut Microbiome

Chairmen: Dr Michael Cheung & Dr Loey Mak

1. Gut Microbiota in Metabolic Health and Disease - Prof Aimin Xu, Professor, Chair of Metabolic Medicine, Department of Medicine

2. Indispensable Exposome-Microbiome-Immunity alliance in health and diseases - Dr Hein Min Tun, Assistant Professor, School of Public Health, HKU

3. Metagenomic analysis of the gut microbiome - Dr Joshua Ho, Associate Professor, School of Biomedical Sciences, HKU
12:50 – 14:00
Luncheon
e-Poster abstracts - Oral Session - 13:00 – 14:00
Clinical Research
Basic Science & Translational Research
Chairmen:
Dr Gary Lau
Dr Paul Lee
Chairmen:
Dr Danny Wong
Dr Susan Yung
14:00 – 14:30

Plenary Session

Chairman: Prof Anskar Leung

Understanding Innate Immunity in Alzheimer's Disease – Insights for Development of Therapeutics

Prof Nancy Ip, Vice-President for Research and Development, The Morningside Professor of Life Science and Director of the State Key Laboratory of Molecular Neuroscience, HKUST
14:30 – 15:30

Artificial Intelligence

Chairmen: Dr Ho-Yin Chung & Dr Desmond Yap

1. Online COVID-19 diagnosis with chest CT images: Lesion-attention deep neural networks - Prof Guosheng Yin, Patrick S C Poon Professor in Statistics and Actuarial Science and Head of Department, Department of Statistics & Actuarial Science, HKU

2. Potential and challenges of developing AI models for medical imaging - Dr Keith Chiu, Clinical Assistant Professor, Department of Diagnostic Radiology, HKU

3. Medical image analysis using machine learning - Dr Kenneth Wong, Associate Professor, Department of Computer Science, HKU

15:30 – 16:10

Clinical Trial Design

Chairmen: Dr Joanne Chiu & Dr Judith Mak

1. Clinical Trial Designs - Dr Helen Zhi, Director, Biostatistics and Clinical Research Methodology Unit, School of Public Health, HKU

2. Cost-effectiveness analysis alongside clinical trials: why and how? - Dr Shirley Li, Assistant Professor, Department of Medicine, HKU
16:10 – 16:30
Break
16:30 – 17:10

Drug Delivery

Chairmen: Dr Joanne Chiu & Dr Judith Mak

1. Metallodrugs as antimicrobial agents: from antimicrobial resistance (AMR) to anti SARS-Cov-2 - Prof Hongzhe Sun, Chair Professor and Norman and Cecilia Yip Professor in Bioinorganic Chemistry, Department of Chemistry, HKU

2. Delivery of nucleic acids and other biopharmaceuticals using the pulmonary route - Dr Jenny Lam, Associate Head (Undergraduate Education) and Associate Professor, Department of Pharmacology and Pharmacy, HKU

17:10 – 18:00

Oral Session

Chairmen: Dr Philip Li & Dr Jacqueline Yuen

Basic Science & Translational Research

  1. Novel therapeutic effects and mechanisms of Polo-like kinase 4 inhibition in acute myeloid leukaemia - Mr Chee Chean Dang

  2. Lactococcus lactis as a fecal biomarker predicting the development of non-alcoholic fatty liver disease: evidence from a human microbiota-associated rodent model - Ms Saisai Zhang

Clinical Research

  1. Thyroid Dysfunction in Relation to Immune Profile, Viral Load, Disease Status and Outcome in 191 Patients with COVID-19 - Dr Tak Wai David Lui

  2. Clinical outcomes in stable coronary artery disease treated with optimal medical therapy alone based on a novel index: computational pressure-flow dynamics derived fractional flow reserve- Ms Kwan Yu Li

18:00 – 18:05
Closing Remarks by Prof Wai Kay Seto, Chairman of 26th MRC


Conference Information

 

Date: January 16, 2021 (Saturday)

Time: 09:00 – 18:00

Format: Virtual Conference

Topics: Basic science, translational and clinical research 

Organiser: Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong 

Language: The official language of the conference is English. There will be no simultaneous translation. 

Continuing Professional Education (CPE) accreditations: Points will be awarded by Hong Kong College of physicians and non-specialists (HKMA, HKDU, HKAM, DH). The completed sheets will be returned to each awarding institution at the completion of the Conference.

Parking: Complimentary parking at the FMB are available for participants however each participant may only be allowed one entry and exit per car per day. Download Road Map   

For enquiries about the Conference, please contact the Conference Secretariat:
Medical Research Conference Secretariat
University Department of Medicine
Room 405, Professorial Block
Queen Mary Hospital
Pok Fu Lam
Hong Kong

Tel: (+852) 2255-6709
Fax: (+852) 2855-1143
Email: medconf@hku.hk
Website: link 

Disclaimer:
Whilst every attempt has been made to ensure that all aspects of the conference announced will take place as scheduled, the Organising Committee reserves the right to make changes at any time should the need arise. 


Program

Past Dates
26th MRC - January 16, 2021 (Saturday) - Program, Poster Presentation List, Presentation Guidelines, Abstract Book, Photos
25th MRC - January 18, 2020 (Saturday) - ProgramPoster Presentation ListPresentation GuidelinesAbstract Book, Photos
24th MRC - January 19, 2019 (Saturday) - ProgramPoster Presentation ListPresentation GuidelinesAbstract Book, Photos
23rd MRC - January 20, 2018 (Saturday) - ProgramPoster Presentation ListPresentation GuidelinesAbstract Book, Photos
22nd MRC - January 14, 2017 (Saturday) - ProgramPoster Presentation ListPresentation Guidelines, Photos
21st MRC - January 16, 2016 (Saturday) - ProgramPoster Presentation ListPresentation Guidelines
20th MRC - January 17, 2015 (Saturday) - ProgramPoster Presentation ListPresentation Guideline
19th MRC - January 18, 2014 (Saturday) - ProgramPoster Presentation ListPresentation Guidelines
18th MRC - January 12, 2013 (Saturday) - ProgramPoster Presentation List,Presentation Guidelines
17th MRC - January 14, 2012 (Saturday) - ProgramPoster Presentation List,Presentation Guidelines