Department of Medicine

RESEARCH

Our research interests include both basic science and clinical topics. The former theme aims to elucidate the pathogenic mechanisms in common or important kidney diseases such as lupus nephritis, diabetic kidney disease, and IgA nephropathy. The latter focuses on advancing treatment to achieve better clinical outcomes in patients.

Research topics in our Division include:

Research Themes	Principal Investigators
Lupus Nephritis Novel immunosuppression and advances in clinical management Immuno-pathogenic mechanisms focusing on renal inflammation and fibrosis	Professor Tak Mao CHAN Prof Susan YUNG Prof Desmond YAP
Diabetic Kidney Disease Role of Toll-like receptor 4 in disease pathogenesis Pathogenic role of proximal tubular epithelial cells in diabetic kidney disease	Professor Sydney TANG Dr Gary CHAN Dr Stella YIU
IgA Nephropathy Glomerulopodocytic-tubular communication Clinical studies including novel immunomodulatory agents	Professor Sydney TANG Professor Tak Mao CHAN
Peritoneal Dialysis Mesothelial cell biology and function Peritoneal membrane inflammation and fibrosis Biocompatibility of peritoneal dialysis fluids Cognitive function Renal nutrition and protein-energy wasting	Prof Susan YUNG Prof Sing Leung LUI Dr Terence YIP Dr Cindy CHOY Prof Desmond YAP Dr Joseph LEUNG Dr Maggie MOK Professor Tak Mao CHAN
Haemodialysis Home haemodialysis Novel technologies	Dr Maggie MOK Dr Lorraine KWAN Professor Tak Mao CHAN
Kidney Transplantation Viral hepatitis Clinical management and outcomes - immunosuppression, recurrent glomerular diseases, CMV and BK virus infections ABO-incompatible transplantation	Prof Tak Mao CHAN Prof Desmond YAP Dr Maggie MA Dr Cindy CHOY Prof Sydney TANG
CKD-MBD and other CKD complications Cardiovascular disease and vascular calcification in patients with chronic kidney disease and dialysis patients Cardiovascular-parathyroid interactions	Dr Maggie Mok Dr Lorraine Kwan Prof Sing Leung LUI Prof Tak Mao CHAN
Sleep Apnea and Kidney Disease Clinical studies on sleep apnea in dialysis or CKD patients	Professor Sydney TANG Dr Gary CHAN
Immunopathogenesis of renal inflammation and fibrosis Role of proteoglycans and glycosaminoglycans in tissue inflammation and fibrosis Fibronectin isoforms in epithelial-to-mesenchymal transition Role of tubular Wnt and β-catenin signaling in renal inflammation Role of stem cells in overload proteinuria	Prof Susan YUNG Professor Tak Mao CHAN Prof Sydney TANG Prof Desmond YAP Dr Stella YIU
Genetic Kidney Diseases	Dr Becky Ma Dr Gary Chan Prof Desmond Yap Prof Sydney Tang Prof Tak Mao Chan’
Traditional Chinese Medicine Integration with Western medicine in the management of chronic kidney disease and diabetic kidney disease	Prof Sing Leung LUI Prof Sydney TANG Prof Susan YUNG Dr Kam Wa CHAN
Renal Supportive or Palliative Care Palliative, psychosocial and supportive management	Dr Terence YIP Dr Kwok Ying CHAN* Prof Sing Leung LUI Prof Desmond YAP Professor Tak Mao CHAN *Palliative Medicine Unit, TGH